Dr. Patrick D. Walker
Dr. Jane M. Bell
Dr. Yihan Wang

Selected Publications by Dr. Patrick D. Walker

  1. P.D.Walker, S.V. Shah: Glomerular Diseases, In Cecil's Essentials of Medicine, 6th Ed., Andreoli, T.E., Carpenter, C.C.J., Griggs, R.C., Loscalzo, J. (eds), W.B. Saunders Co., Philadelphia, Chapter 27, 2004.
  2. J. Kumar, P.D. Walker: Major Nonglomerular Diseases, In Cecil's Essentials of Medicine, 6th Ed., Andreoli, T.E., Carpenter, C.C.J., Griggs, R.C., Loscalzo, J. (eds), W.B. Saunders Co., Philadelphia, Chapter 28, 2004.
  3. W.M. O'Neill, J.D. Wallin, and P.D. Walker. Hematuria and red blood casts in typical diabetic nephropathy. Am. J. Med. 74: 389-395, 1983.
  4. Southwest Pediatric Nephrology Study Group. Childhood nephrotic syndrome associated with diffuse mesangial hypercellularity. Kidney Int. 23: 87-94, 1983.
  5. Focal segmental glomerulosclerosis in children with idiopathic nephrotic syndrome. A report of the Southwest Pediatric Nephrology Study Group. Kidney Int. 27: 442-449, 1985.
  6. A Clinico-pathologic study of Crescentic Glomerulonephritis in 50 Children: A report of the Southwest Pediatric Nephrology Study Group. Kidney Int. 27: 450-458, 1985.
  7. Association of IgA Nephropathy with Steroid-Responsive Nephrotic Syndrome. A report of the Southwest Pediatric Nephrology Study Group. Am. J. Kidney Dis. 5:157-164, 1985.
  8. Dense Deposit Disease in Children: Prognostic Value of Clinical and Pathologic Indicators. A Report of the Southwest Pediatric Nephrology Study Group. Am. J. Kidney Dis. 6:161-169, 1985.
  9. Comparison of idiopathic and systemic lupus erythematosus associated with membranous glomerulonephropathy in children. A Report of the Southwest Pediatric Nephrology Study Group. Am. J. Kidney. Dis. 7:115-124, 1986.10. 
  10. P.D. Walker, S.V. Shah. Gentamicin enhanced production of hydrogen peroxide by renal cortical mitochondria. Am. J. Physiol. 253 (Cell Physiol. 22): C495-C499, 1987.11. 
  11. P.D. Walker, S.V. Shah. Evidence suggesting a role for hydroxyl radical in gentamicin-induced acute renal failure in rats. J. Clin Invest. 81:334-341, 1988.
  12. S. R. Abul-Ezz, P.D. Walker, S. V. Shah. Role of glutathione in an animal model of myoglobinuric acute renal failure. Proc Natl Acad Sci USA 88: 9833-9837, 199113. 
  13. P.D. Walker. Alterations in renal tubular extracellular matrix components after ischemia-reperfusion injury to the kidney. Lab Invest 70:339-346, 1994.
  14. P.D. Walker, G.P. Kaushel and S.V. Shah. Presence of a distinct extracellular matrix degrading metalloproteinase activity in renal tubules. J Am Soc Nephrol 5:55-61, 1994.
  15. G.P. Kaushel, P.D. Walker and S.V. Shah. An old enzyme with a new function: purification and characterization of a distinct matrix-degrading metalloproteinase in rat kidney cortex and its identification as meprin. J Cell Biol 126:1319-1327, 1994.
  16. N. Ueda, P.D. Walker, S-M. Hsu and S.V. Shah. Activation of a 15 kDa endonuclease in hypoxia/reoxygenation injury without morphologic features of apoptosis. Proc Natl Acad Sci USA 92:7202-7206 1995.
  17. P.D. Walker, G.P. Kaushel and S.V. Shah. Meprin A, the major matrix degrading enzyme in kidney, produces a novel nidogen fragment in vitro and in vivo. Kidney Int 53: 1673-1680, 1998.
  18. I. Ahmad, S.R. Abul-Ezz,., P.D. Walker, S.M. Bonsib, B. Ketel, Y..M. Barri. Acute rejection presenting as nephrotic syndrome. Transplantation. 69(12):2663-5, 2000 Jun 27
  19. S.M. Bonsib, S.R. Abul-Ezz, I. Ahmad, S.M. Young, E.N.Ellis, D. L. Schneider, P.D. Walker: Acute rejection associated tubular basement membrane defects and chronic allograft nephropathy. Kidney Int 58: 2206-2214, 2000.
  20. YM Barri, Ahmad, I., Ketel, B., Barone, G., Bonsib, S.M., Walker, P.D. Abul-Ezz, S.R. Polyoma viral infection in renal transplantion: the role of immunosuppressive therapy. Clin Transplant 15: 240-6, 2001
  21. N Ueda, Camargo S, Basnakian A, Hong X, Walker PD, Shah SV. Role of ceramide synthase in oxidant injury to renal tubular epithelial cells. J Am Soc Nephrol 12: 2384-91, 2001
  22. Carmago, S., Shah, S.V., Walker, P.D.. Meprin, a brush border enzyme, plays an important role in hypoxic/ischemic acute renal failure. Kidney Int 61: 959-966, 2002
  23. Hoschek, J.C., Dreyer, P., Dahal, S., Walker, P.D.: Rapidly progressive renal failure in childhood. Am J Kid Dis 40: 1342-1347, 2002
  24. Barri, Y. M., Munshi, N. C., Sukumalchantra, S., Abulezz, S. R., Bonsib, S.M. Wallach, J. Walker, P.D. Podocyte injury associated glomerulopathies induced by pamidronate. Kidney Int: 65: 634-641, 2004
  25. Nair, R., Bell, J. M., Walker, P.D. Renal biopsy in patients aged 80 years and older. Am J Kid Dis 44:618-626, 200426. 
  26. Walker, P.D., Cavallo, T., Bonsib, S.M. Practice guidelines for the renal biopsy, Modern Pathol 17: 1555-1563, 2004
  27. Nair, R., Bell, J. M. Walker, P.D. Diabetic female with massive proteinuria and acute renal failure. Accepted for publication, February 2005 Am J Kid Dis

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Selected Publications by Dr. Jane M. Bell

  1. Kraja-Radcliffe J, Nicholas R, *Lewis JM: Epithelioid Hemangioendothelioma of Bone: A Case Report and Review of the Literature. Orthopedic Review XXI (8):973-980, 1992.
  2. Sawyer JR, Tryka AF, *Lewis JM: A Novel Reciprocal Chromosome Translocation t (11;22) (p13;q12) in an Intraabdominal Desmoplastic Small Round-Cell Tumor. American Journal of Surgical Pathology 16(4):411-416, 1992.
  3. Sawyer JR, Sammartino GM, Husain M, *Lewis JM, Anderson B, Boop FA: Ring Chromosome 12 Resulting from Non-random Telomeric Association of Chromosome 15p in a Cerebellar Astrocytoma. Genes, Chromosomes, and Cancer, 8:69-73, 1993.
  4. Sawyer JR, Sammartino GM, Baker GF, Bell JM: Clonal Chromosome Aberrations in a case of Nodular Fasciitis. Cancer Genetics and Cytogenetics 76(2):154-6, 1994.
  5. Sawyer JR, Parsons EA, Crowson ML, Smith S, Erickson S, Bell JM: Potential Diagnostic Implications of Breakpoints in the Long Arm of Chromosome 8 in Lipoblastoma. Cancer Genetics and Cytogenetics 76:39-42, 1994.
  6. Dunlap J, Maxon RT, James C, Bell JM, Wagner C: Gastric Teratoma with Intramural Extension. Pediatric Radiology 25(5):383-4, 1995.
  7. Sawyer JR, Roloson GJ, Bell JM, Thomas JR, Teo C, Chadduck WM: Telomeric Associations in the Progression of Chromosome Aberrations in Pediatric Solid Tumors. Cancer Genetics and Cytogenetics 90(1): 1-13, 1996.
  8. Allison JW, James CA, Arnold GL, Stine KC, Becton DL, Bell JM: Reconversion of Bone Marrow in Gaucher Disease Treated with Enzyme Therapy Documented by MR. Pediatric Radiology (4):237-40, 1998.
  9. Bell J.M., Nair, R., Walker, P.D.: SLE: the great imitator strikes again. Am J Kid Dis 45:219-222, 2005.

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Selected Publications by Dr. Yihan Wang

  1. Wang YH, Huang WQ, Xu B, Yu ZM. Effects of isovolemic hemodilution on myocardial ischemia in dogs. Chin J Appl Physiol. 1989 5(3): 295-299.
  2. Wang YH. One book chapter: “A manual on kymograph operation and maintenance” in the book of Manual of Physiological Experiments. Suzhou Medical School Publishing Inc, 1989.
  3. Chen YF, Wang YH, Yin QZ. The role of paraventricular nucleus of hypothalamus in acupuncture analgesia in rats. Acupuncture Research. 1991 16(1): 32-38.4.           
  4. Wang YH, etc. Translation of 11 chapters from English to Chinese in the book “Encyclopedia of Neuroscience”. Birkhauser Inc. and Shanghai Publishing Inc. of Science and Technique, 1992.
  5. Li ZY, Wang YH, Maldonado C, Kupersmith J. Role of junctional zone cells between Purkinje fibers and ventricular muscle in arrhythmogenesis. Cardiovasc Res. 1994 Aug; 28(8): 1277-84.
  6. Xia F, Wang X, Wang YH, Tsang NM, Yandell DW, Kelsey KT, Liber HL. Altered p53 status correlates with differences in sensitivity to radiation-induced mutation and apoptosis in two closely related human lymphoblast lines. Cancer Res. 1995 Jan 1; 55(1): 12-5.7.
  7. Wang YH, Borkan SC. Prior heat stress enhances survival of renal epithelial cells after ATP depletion. Am J Physiol. 1996 Jun; 270(6 Pt 2): F1057-65.
  8. Borkan SC, Wang YH, Lam KT, Brecher P, Schwartz JH. Hepatic alpha 2 mu-globulin: a potential metabolic role in the rat proximal tubule. Am J Physiol. 1996 Sep; 271(3 Pt 2): F527-38.
  9. Borkan SC, Wang YH, Lieberthal W, Burke PR, Schwartz JH. Heat stress ameliorates ATP depletion-induced sublethal injury in mouse proximal tubule cells. Am J Physiol. 1997 Mar; 272(3 Pt 2): F347-55.
  10. Cantiello HF, Jackson GR Jr, Grosman CF, Prat AG, Borkan SC, Wang Y, Reisin IL, O'Riordan CR, Ausiello DA. Electrodiffusional ATP movement through the cystic fibrosis transmembrane conductance regulator. Am J Physiol. 1998 Mar; 274(3 Pt 1): C799-809.
  11. Obrador G, Yuan H, Shih TM, Wang YH, Shia MA, Alexander EA, Schwartz JH. Characterization of anion exchangers in an inner medullary collecting duct cell line. J Am Soc Nephrol. 1998 May; 9(5): 746-54.
  12. Wang Y, Knowlton AA, Christensen TG, Shih T, Borkan SC. Prior heat stress inhibits apoptosis in adenosine triphosphate-depleted renal tubular cells. Kidney Int. 1999 Jun; 55(6): 2224-35.
  13. Prat AG, Cunningham CC, Jackson GR Jr, Borkan SC, Wang Y, Ausiello DA, Cantiello HF. Actin filament organization is required for proper cAMP-dependent activation of CFTR. Am J Physiol. 1999 Dec; 277(6 Pt 1): C1160-9.
  14. Lader AS, Wang Y, Jackson GR Jr, Borkan SC, Cantiello HF. cAMP-activated anion conductance is associated with expression of CFTR in neonatal mouse cardiac myocytes. Am J Physiol Cell Physiol. 2000 Feb; 278(2): C436-50.15
  15. Wang Y, Shia MA, Christensen TG, Borkan SC. Hepatic alpha 2 microglobulin localizes to the cytosol of rat proximal tubule cells. Kidney Int. 2000 Mar; 57(3): 1015-26.
  16. Wang YH, Li F, Schwartz JH, Flint PJ, Borkan SC. c-Src and HSP72 interact in ATP-depleted renal epithelial cells. Am J Physiol Cell Physiol. 2001 Nov; 281(5): C1667-75.
  17. Li F, Mao HP, Ruchalski KL, Wang YH, Choy W, Schwartz JH, Borkan SC. Heat stress prevents mitochondrial injury in ATP-depleted renal epithelial cells. Am J Physiol Cell Physiol. 2002 Sep; 283(3): C917-26.
  18. Wang YH, Knowlton AA, Li FH, Borkan SC. Hsp72 expression enhances survival in adenosine triphosphate-depleted renal epithelial cells. Cell Stress Chaperones. 2002 Apr; 7(2): 137-45.
  19. Mao H, Yu XQ, Li ZJ, Yang QQ, Yin PD, Li FH, , Ruchalski K, Schwartz JH, Borkan SC, and Wang Y. The role of cytochrome c release in ATP depletion-induced renal epithelial apoptosis. Chin J Nephrol. 2003 19(2): 90-94.
  20. Mao H, Yu XQ, Yang QQ, Yin PD, Li FH, Ruchalski K, Schwartz JH, Borkan SC, and Wang Y. Heat stress protein 72 inhibits cytochrome c release during chemical ischemia in renal epithelial cells. Chin J Nephrol. 2003 19(3): 6-10.
  21. Mao H, Li F, Ruchalski K, Mosser DD, Schwartz JH, Wang Y, Borkan SC. Hsp72 inhibits focal adhesion kinase degradation in ATP-depleted renal epithelial cells. J Biol Chem. 2003 May 16; 278(20): 18214-20. Epub 2003 Feb 28.
  22. Ruchalski K, Mao H, Singh SK, Wang Y, Mosser DD, Li F, Schwartz JH, Borkan SC. HSP72 inhibits apoptosis-inducing factor release in ATP-depleted renal epithelial cells. Am J Physiol Cell Physiol. 2003 Dec; 285(6): C1483-93. Epub 2003 Aug 20.
  23. Mao H, Wang Y (co-first authorship), Li Z, Ruchalski KL, Yu X, Schwartz JH, Borkan SC. Hsp72 interacts with paxillin and facilitates the reassembly of focal adhesions during recovery from ATP depletion. J Biol Chem. 2004 Apr 9; 279(15): 15472-80. Epub 2004 Jan 12.
  24. Wang Y, Rossini M, Fogo AB. Quiz page. HIV-associated nephropathy is the overwhelmingly most likely diagnosis. Am J Kidney Dis. 2004 Apr; 43(4): A47, e1.
  25. Wang Y, Fogo AB. Quiz page. Anti-GBM antibody-mediated glomerulonephritis with superimposed ANCA-associated vasculitis. Am J Kidney Dis. 2004 Sep; 44(3): A45, e31-2.26.
  26. Wang Y, Fogo AB. Chapter 12: Histopathologic patterns in hypertensive nephrosclerosis in African Americans. In book Kidney Diseases in the Developing World and Ethic Minorities. Marcel Decker, Inc. 2005, p267-283.
  27. Qi ZH, Fujita H, Jin JP, Davis LS, Wang YH, Fogo AB, Breyer MD. Characterization of susceptibility of inbred mouse strains to diabetic nephropathy. Diabetes, 2005. (in press)

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